2026 Mercedes-Benz S 500 4MATIC® Sedan vs S 580 4MATIC Sedan
The S 580 4MATIC makes 496 horsepower, a 67-horsepower advantage over the S 500 4MATIC. That difference comes from the V8 biturbo engine in the higher trim. Browse our new Mercedes-Benz S-Class inventory to find the powertrain that suits you.

Engineering and Performance
Choosing the right S-Class starts with the engine. For the full lineup, review our 2026 S-Class overview. The S 500 4MATIC uses a 3.0-liter inline-6 turbo with mild-hybrid drive, producing 429 horsepower and 384 lb-ft for seamless, quiet acceleration when merging onto I-20/59. The S 580 4MATIC steps up to a 4.0-liter V8 biturbo with mild-hybrid drive, making 496 horsepower and 516 lb-ft for effortless passing with minimal throttle input. To feel the difference, explore our available S 500 and S 580 sedans.
| Specification | S 500 4MATIC® Sedan | S 580 4MATIC® Sedan |
|---|---|---|
| Engine | 3.0L inline-6 turbo (mild hybrid) | 4.0L V8 biturbo (mild hybrid) |
| Horsepower | 429 hp | 496 hp |
| Torque | 384 lb-ft | 516 lb-ft |
| 0 to 60 mph | About 4.7 seconds | About 4.3 seconds |

Handling and Ride Quality
Both sedans come standard with AIRMATIC® air suspension that continuously adapts to the road for a vibration-free ride, smoothing uneven pavement near the Black Warrior River. Standard 4MATIC® all-wheel drive distributes torque dynamically for confident grip during sudden southern rainstorms. You can review further details on the S 580 page at Mercedes-Benz USA and the S 500 page.

Interior Refinement
The cabin dimensions and luxury appointments are the same across both core configurations, including heavily insulated acoustic glass and available multi-contour front seats with massage.
Whether you choose the inline-6 or the V8, the focus on comfort and quiet is identical, so the decision really comes down to how much power and character you want. Our team can arrange a back-to-back drive so you can feel the difference before you decide.
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